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Hormone and Drug-Mediated Modulation of Glucose Metabolism in a Microscale Model of the Human Liver

Due to its central role in glucose homeostasis, the liver is an important target for drug development efforts for type 2 diabetes mellitus (T2DM). Significant differences across species in liver metabolism necessitate supplementation of animal data with assays designed to assess human-relevant respo...

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Detalhes bibliográficos
Publicado no:Tissue Eng Part C Methods
Main Authors: Davidson, Matthew D., Lehrer, Michael, Khetani, Salman R.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499785/
https://ncbi.nlm.nih.gov/pubmed/25517416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tec.2014.0512
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