Block of T lymphocyte differentiation by activation of the cAMP-dependent signal transduction pathway.

Differentiation of T lymphocytes is a complex and finely tuned process. Here we show that treatment of mouse fetal thymus organ cultures with agents activating the cAMP-dependent signalling pathway results in the block of thymocyte differentiation. This is due to severe impairment of maturation beyo...

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Библиографические подробности
Главные авторы: Lalli, E, Sassone-Corsi, P, Ceredig, R
Формат: Artigo
Язык:Inglês
Опубликовано: 1996
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC449971/
https://ncbi.nlm.nih.gov/pubmed/8599936
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