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Cultured lymphocytes from alcoholic subjects have altered cAMP signal transduction.

Previous work has shown that freshly isolated lymphocytes from alcoholic subjects show significantly reduced basal and adenosine receptor-stimulated cAMP levels. This decrease could be due to ethanol-induced cellular adaptation or to a genetic difference in the regulation of cAMP signal transduction...

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Bibliographic Details
Main Authors: Nagy, L E, Diamond, I, Gordon, A
Format: Artigo
Language:Inglês
Published: 1988
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC282101/
https://ncbi.nlm.nih.gov/pubmed/2842798
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