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A surrogate-primary replacement algorithm for response-adaptive randomization in stroke clinical trials

Response-adaptive randomization (RAR) offers clinical investigators benefit by modifying the treatment allocation probabilities to optimize the ethical, operational, or statistical performance of the trial. Delayed primary outcomes and their effect on RAR have been studied in the literature; however...

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Detalhes bibliográficos
Publicado no:Stat Methods Med Res
Main Authors: Nowacki, Amy S, Zhao, Wenle, Palesch, Yuko Y
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499496/
https://ncbi.nlm.nih.gov/pubmed/25586325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280214567142
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