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Managing competing demands in the implementation of response-adaptive randomization in a large multi-center phase III acute stroke trial

It is well known that competing demands exist between the control of important covariate imbalance and protection of treatment allocation randomness in confirmative clinical trials. When implementing a response-adaptive randomization algorithm in confirmative clinical trials designed under a frequen...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Zhao, Wenle, Durkalski, Valerie
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159417/
https://ncbi.nlm.nih.gov/pubmed/24849843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6213
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