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Altered Morphine Glucuronide and Bile Acid Disposition in Patients with Non-Alcoholic Steatohepatitis

The functional impact of altered drug transport protein expression on the systemic pharmacokinetics of morphine, hepatically-derived morphine glucuronide (morphine-3- and morphine-6-glucuronide), and fasting bile acids was evaluated in patients with biopsy-confirmed non-alcoholic steatohepatitis (NA...

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Vydáno v:Clin Pharmacol Ther
Hlavní autoři: Ferslew, Brian C., Johnston, Curtis K., Tsakalozou, Eleftheria, Bridges, Arlene S., Paine, Mary F., Jia, Wei, Stewart, Paul W., Barritt, A. Sidney, Brouwer, Kim L.R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499311/
https://ncbi.nlm.nih.gov/pubmed/25669174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.66
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