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Direct Sensing of 5-Methylcytosine by Polymerase Chain Reaction**

The epigenetic control of genes by the methylation of cytosine resulting in 5-methylcytosine (5mC) has fundamental implications for human development and disease. Analysis of alterations in DNA methylation patterns is an emerging tool for cancer diagnostics and prognostics. Here we report that two t...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Aschenbrenner, Joos, Drum, Matthias, Topal, Hüsnü, Wieland, Markus, Marx, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499253/
https://ncbi.nlm.nih.gov/pubmed/24923910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201403745
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