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5-methylcytosine-sensitive variants of Thermococcus kodakaraensis DNA polymerase

DNA methylation of cytosine in eukaryotic cells is a common epigenetic modification, which plays an important role in gene expression and thus affects various cellular processes like development and carcinogenesis. The occurrence of 5-methyl-2′-deoxycytosine (5mC) as well as the distribution pattern...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Huber, Claudia, von Watzdorf, Janina, Marx, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175357/
https://ncbi.nlm.nih.gov/pubmed/27651460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw812
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