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Cell-Permeant and Photocleavable Chemical Inducer of Dimerization**
Chemical inducers of dimerization (CIDs) have been developed to orchestrate protein dimerization and translocation. Here we present a novel photocleavable HaloTag- and SNAP-tag-reactive CID (MeNV-HaXS) with excellent selectivity and intracellular reactivity. Excitation at 360 nm cleaves the methyl-6...
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| Publié dans: | Angew Chem Int Ed Engl |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
WILEY-VCH Verlag
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4499241/ https://ncbi.nlm.nih.gov/pubmed/24677313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201310969 |
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