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Photocleavable Dimerizer for the Rapid Reversal of Molecular Trap Antagonists
Herein, we report the development of a photocleavable analog of AP20187, a cell-permeable molecule used to dimerize FK506-binding protein (FKBP) fusion proteins and initiate biological signaling cascades and gene expression or disrupt protein-protein interactions. We demonstrate that this reagent pe...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3931014/ https://ncbi.nlm.nih.gov/pubmed/24421317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C113.513622 |
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