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The Cas6e ribonuclease is not required for interference and adaptation by the E. coli type I-E CRISPR-Cas system

CRISPR-Cas are small RNA-based adaptive prokaryotic immunity systems protecting cells from foreign DNA or RNA. Type I CRISPR-Cas systems are composed of a multiprotein complex (Cascade) that, when bound to CRISPR RNA (crRNA), can recognize double-stranded DNA targets and recruit the Cas3 nuclease to...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Semenova, Ekaterina, Kuznedelov, Konstantin, Datsenko, Kirill A., Boudry, Pierre M., Savitskaya, Ekaterina E., Medvedeva, Sofia, Beloglazova, Natalia, Logacheva, Maria, Yakunin, Alexander F., Severinov, Konstantin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499155/
https://ncbi.nlm.nih.gov/pubmed/26013814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv546
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