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ATP-dependent G-quadruplex unfolding by Bloom helicase exhibits low processivity

Various helicases and single stranded DNA (ssDNA) binding proteins unfold G-quadruplex (GQ) structures. However, the underlying mechanisms of this activity have only recently come to focus. We report kinetic studies on Bloom (BLM) helicase and human telomeric GQ interactions using single-molecule Fö...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Budhathoki, Jagat B., Stafford, Edward J., Yodh, Jaya G., Balci, Hamza
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499149/
https://ncbi.nlm.nih.gov/pubmed/25990739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv531
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