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ATP-dependent G-quadruplex unfolding by Bloom helicase exhibits low processivity
Various helicases and single stranded DNA (ssDNA) binding proteins unfold G-quadruplex (GQ) structures. However, the underlying mechanisms of this activity have only recently come to focus. We report kinetic studies on Bloom (BLM) helicase and human telomeric GQ interactions using single-molecule Fö...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4499149/ https://ncbi.nlm.nih.gov/pubmed/25990739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv531 |
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