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ATP-dependent G-quadruplex unfolding by Bloom helicase exhibits low processivity
Various helicases and single stranded DNA (ssDNA) binding proteins unfold G-quadruplex (GQ) structures. However, the underlying mechanisms of this activity have only recently come to focus. We report kinetic studies on Bloom (BLM) helicase and human telomeric GQ interactions using single-molecule Fö...
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| Publicado en: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4499149/ https://ncbi.nlm.nih.gov/pubmed/25990739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv531 |
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