Systematic Analysis of the Protein Interaction Network for the Human Transcription Machinery Reveals the Identity of the 7SK Capping Enzyme

We have performed a survey of soluble human protein complexes containing components of the transcription and RNA processing machineries using protein affinity purification coupled to mass spectrometry. Thirty-two tagged polypeptides yielded a network of 805 high-confidence interactions. Remarkably,...

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Vydáno v:Mol Cell
Hlavní autoři: Jeronimo, Célia, Forget, Diane, Bouchard, Annie, Li, Qintong, Chua, Gordon, Poitras, Christian, Thérien, Cynthia, Bergeron, Dominique, Bourassa, Sylvie, Greenblatt, Jack, Chabot, Benoit, Poirier, Guy G., Hughes, Timothy R., Blanchette, Mathieu, Price, David H., Coulombe, Benoit
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498903/
https://ncbi.nlm.nih.gov/pubmed/17643375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.06.027
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