Neutrophil Extracellular Traps are Involved in the Innate Immune Response to Infection with Leptospira

NETosis is a process by which neutrophils extrude their DNA together with bactericidal proteins that trap and/or kill pathogens. In the present study, we evaluated the ability of Leptospira spp. to induce NETosis using human ex vivo and murine in vivo models. Microscopy and fluorometric studies show...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Scharrig, Emilia, Carestia, Agostina, Ferrer, María F., Cédola, Maia, Pretre, Gabriela, Drut, Ricardo, Picardeau, Mathieu, Schattner, Mirta, Gómez, Ricardo M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498591/
https://ncbi.nlm.nih.gov/pubmed/26161745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003927
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