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Decay-Accelerating Factor 1 Deficiency Exacerbates Leptospiral-Induced Murine Chronic Nephritis and Renal Fibrosis

Leptospirosis is a global zoonosis caused by pathogenic Leptospira, which can colonize the proximal renal tubules and persist for long periods in the kidneys of infected hosts. Here, we characterized the infection of C57BL/6J wild-type and Daf1(−/−) mice, which have an enhanced host response, with a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ferrer, María F., Scharrig, Emilia, Alberdi, Lucrecia, Cedola, Maia, Pretre, Gabriela, Drut, Ricardo, Song, Wen-Chao, Gomez, Ricardo M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102560/
https://ncbi.nlm.nih.gov/pubmed/25032961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102860
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