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Delivery of Antibody Mimics into Mammalian Cells via Anthrax Toxin Protective Antigen

Antibody mimics have significant scientific and therapeutic utility for the disruption of protein–protein interactions inside cells; however, their delivery to the cell cytosol remains a major challenge. Here we show that protective antigen (PA), a component of anthrax toxin, efficiently transports...

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Bibliographic Details
Published in:Chembiochem
Main Authors: Liao, Xiaoli, Rabideau, Amy E, Pentelute, Bradley L
Format: Artigo
Language:Inglês
Published: WILEY-VCH Verlag 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498471/
https://ncbi.nlm.nih.gov/pubmed/25250705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402290
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