Poly(lactide-co-glycolide) Microspheres for MRI-Monitored Delivery of Sorafenib in a Rabbit VX2 model

Transcatheter arterial embolization and chemoembolization are standard locoregional therapies for hepatocellular carcinoma (HCC). However, these can result in tumor hypoxia, thus promoting tumor angiogenesis. The anti-angiogenic agent sorafenib is hypothesized to improve outcomes; however, oral admi...

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Bibliographic Details
Published in:Biomaterials
Main Authors: Chen, Jeane, White, Sarah B., Harris, Kathleen R., Li, Weiguo, Yap, Jonathan WT, Kim, Dong-Hyun, Lewandowski, Robert J., Shea, Lonnie D., Larson, Andrew C.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498403/
https://ncbi.nlm.nih.gov/pubmed/26022791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.05.010
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