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Poly(ethylene glycol)-Modified Proteins: Implications for Poly(lactide-co-glycolide)-Based Microsphere Delivery

The reduced injection frequency and more nearly constant serum concentrations afforded by sustained release devices have been exploited for the chronic delivery of several therapeutic peptides via poly(lactide-co-glycolide) (PLG) microspheres. The clinical success of these formulations has motivated...

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Hlavní autoři: Pai, Sheetal S., Tilton, Robert D., Przybycien, Todd M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664882/
https://ncbi.nlm.nih.gov/pubmed/19199044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-009-9081-8
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