A Nanotechnology-Based Platform for Extending the Pharmacokinetic and Binding Properties of Anti-methamphetamine Antibody Fragments

To address the need for effective medications to aid in the treatment of methamphetamine (METH) abuse, we used a nanotechnology approach to customize the in vivo behavior of an anti-METH single chain antibody (scFv7F9Cys). Anti-METH scFv7F9Cys was conjugated to dendrimer nanoparticles via a polyethy...

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Udgivet i:Sci Rep
Main Authors: Nanaware-Kharade, Nisha, Thakkar, Shraddha, Gonzalez III, Guillermo A., Peterson, Eric C.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498229/
https://ncbi.nlm.nih.gov/pubmed/26159352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12060
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