Human CLC-K Channels Require Palmitoylation of Their Accessory Subunit Barttin to Be Functional

CLC-K/barttin chloride channels are essential for NaCl re-absorption in Henle's loop and for potassium secretion by the stria vascularis in the inner ear. Here, we studied the posttranslational modification of such channels by palmitoylation of their accessory subunit barttin. We found that bar...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Steinke, Kim Vanessa, Gorinski, Nataliya, Wojciechowski, Daniel, Todorov, Vladimir, Guseva, Daria, Ponimaskin, Evgeni, Fahlke, Christoph, Fischer, Martin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2015
Gaiak:
Membrane Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498076/
https://ncbi.nlm.nih.gov/pubmed/26013830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.631705
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