Human CLC-K Channels Require Palmitoylation of Their Accessory Subunit Barttin to Be Functional

CLC-K/barttin chloride channels are essential for NaCl re-absorption in Henle's loop and for potassium secretion by the stria vascularis in the inner ear. Here, we studied the posttranslational modification of such channels by palmitoylation of their accessory subunit barttin. We found that bar...

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Publicat a:J Biol Chem
Autors principals: Steinke, Kim Vanessa, Gorinski, Nataliya, Wojciechowski, Daniel, Todorov, Vladimir, Guseva, Daria, Ponimaskin, Evgeni, Fahlke, Christoph, Fischer, Martin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
Matèries:
Membrane Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498076/
https://ncbi.nlm.nih.gov/pubmed/26013830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.631705
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