Human CLC-K Channels Require Palmitoylation of Their Accessory Subunit Barttin to Be Functional

CLC-K/barttin chloride channels are essential for NaCl re-absorption in Henle's loop and for potassium secretion by the stria vascularis in the inner ear. Here, we studied the posttranslational modification of such channels by palmitoylation of their accessory subunit barttin. We found that bar...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Steinke, Kim Vanessa, Gorinski, Nataliya, Wojciechowski, Daniel, Todorov, Vladimir, Guseva, Daria, Ponimaskin, Evgeni, Fahlke, Christoph, Fischer, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Membrane Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498076/
https://ncbi.nlm.nih.gov/pubmed/26013830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.631705
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