Human CLC-K Channels Require Palmitoylation of Their Accessory Subunit Barttin to Be Functional

CLC-K/barttin chloride channels are essential for NaCl re-absorption in Henle's loop and for potassium secretion by the stria vascularis in the inner ear. Here, we studied the posttranslational modification of such channels by palmitoylation of their accessory subunit barttin. We found that bar...

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Publicado en:J Biol Chem
Autores principales: Steinke, Kim Vanessa, Gorinski, Nataliya, Wojciechowski, Daniel, Todorov, Vladimir, Guseva, Daria, Ponimaskin, Evgeni, Fahlke, Christoph, Fischer, Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Membrane Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498076/
https://ncbi.nlm.nih.gov/pubmed/26013830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.631705
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