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Human CLC-K Channels Require Palmitoylation of Their Accessory Subunit Barttin to Be Functional

CLC-K/barttin chloride channels are essential for NaCl re-absorption in Henle's loop and for potassium secretion by the stria vascularis in the inner ear. Here, we studied the posttranslational modification of such channels by palmitoylation of their accessory subunit barttin. We found that bar...

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Foilsithe in:J Biol Chem
Main Authors: Steinke, Kim Vanessa, Gorinski, Nataliya, Wojciechowski, Daniel, Todorov, Vladimir, Guseva, Daria, Ponimaskin, Evgeni, Fahlke, Christoph, Fischer, Martin
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498076/
https://ncbi.nlm.nih.gov/pubmed/26013830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.631705
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