Lipid and Carbohydrate Modifications of α-Galactosylceramide Differently Influence Mouse and Human Type I Natural Killer T Cell Activation

The ability of different glycosphingolipids (GSLs) to activate type I natural killer T cells (NKT cells) has been known for 2 decades. The possible therapeutic use of these GSLs has been studied in many ways; however, studies are needed in which the efficacy of promising GSLs is compared under ident...

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Foilsithe in:J Biol Chem
Main Authors: Birkholz, Alysia, Nemčovič, Marek, Yu, Esther Dawen, Girardi, Enrico, Wang, Jing, Khurana, Archana, Pauwels, Nora, Farber, Elisa, Chitale, Sampada, Franck, Richard W., Tsuji, Moriya, Howell, Amy, Van Calenbergh, Serge, Kronenberg, Mitchell, Zajonc, Dirk M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2015
Ábhair:
Immunology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498060/
https://ncbi.nlm.nih.gov/pubmed/26018083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.654814
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