Glucocorticoid-mediated co-regulation of RCAN1-1, E4BP4 and BIM in human leukemia cells susceptible to apoptosis

Glucocorticoids (GCs) are known to induce apoptosis of leukemia cells via gene regulatory changes affecting key pro-and anti-apoptotic genes. Three genes previously implicated in GC-evoked apoptosis in the CEM human T-cell leukemia model, RCAN1, E4BP4 and BIM, were studied in a panel of human lympho...

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Bibliographic Details
Published in:Biochem Biophys Res Commun
Main Authors: Saenz, G. Jonatan, Hovanessian, Rebeka, Gisis, Andrew D., Medh, Rheem D.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497928/
https://ncbi.nlm.nih.gov/pubmed/26102033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.06.106
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