FAM96A is a Novel Pro-Apoptotic Tumor Suppressor in Gastrointestinal Stromal Tumors

The ability to escape apoptosis is a hallmark of cancer-initiating cells and a key factor of resistance to oncolytic therapy. Here, we identify FAM96A as a ubiquitous, evolutionarily conserved apoptosome-activating protein and investigate its potential pro-apoptotic tumor suppressor function in gast...

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Publicat a:Int J Cancer
Autors principals: Schwamb, Bettina, Pick, Robert, Fernández, Sara Beatriz Mateus, Völp, Kirsten, Heering, Jan, Dötsch, Volker, Bösser, Susanne, Jung, Jennifer, Beinoraviciute-Kellner, Rasa, Wesely, Josephine, Zörnig, Inka, Hammerschmidt, Matthias, Nowak, Matthias, Penzel, Roland, Zatloukal, Kurt, Joos, Stefan, Rieker, Ralf Joachim, Agaimy, Abbas, Söder, Stephan, Reid-Lombardo, KMarie, Kendrick, Michael L., Bardsley, Michael R., Hayashi, Yujiro, Asuzu, David T., Syed, Sabriya A., Ordog, Tamas, Zörnig, Martin
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497860/
https://ncbi.nlm.nih.gov/pubmed/25716227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29498
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