Overexpression of the Far Upstream Element Binding Protein 1 in Hepatocellular Carcinoma Is Required for Tumor Growth

We identified the far upstream element binding protein 1 (FBP1), an activator of transcription of the proto-oncogene c-myc, in a functional yeast survival screen for tumor-related antiapoptotic proteins and demonstrated strong overexpression of FBP1 in human hepato-cellular carcinoma (HCC). Knockdow...

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Hlavní autoři: Rabenhorst, Uta, Beinoraviciute-Kellner, Rasa, Brezniceanu, Marie-Luise, Joos, Stefan, Devens, Frauke, Lichter, Peter, Rieker, Ralf J., Trojan, Jörg, Chung, Hye-Jung, Levens, David L., Zörnig, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474328/
https://ncbi.nlm.nih.gov/pubmed/19637194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23098
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