A Functional Yeast Survival Screen of Tumor-Derived cDNA Libraries Designed to Identify Anti-Apoptotic Mammalian Oncogenes

Yeast cells can be killed upon expression of pro-apoptotic mammalian proteins. We have established a functional yeast survival screen that was used to isolate novel human anti-apoptotic genes overexpressed in treatment-resistant tumors. The screening of three different cDNA libraries prepared from m...

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Bibliografische gegevens
Hoofdauteurs: Eißmann, Moritz, Schwamb, Bettina, Melzer, Inga Maria, Moser, Julia, Siele, Dagmar, Köhl, Ulrike, Rieker, Ralf Joachim, Wachter, David Lukas, Agaimy, Abbas, Herpel, Esther, Baumgarten, Peter, Mittelbronn, Michel, Rakel, Stefanie, Kögel, Donat, Böhm, Stefanie, Gutschner, Tony, Diederichs, Sven, Zörnig, Martin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661464/
https://ncbi.nlm.nih.gov/pubmed/23717670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064873
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