A Functional Yeast Survival Screen of Tumor-Derived cDNA Libraries Designed to Identify Anti-Apoptotic Mammalian Oncogenes

Yeast cells can be killed upon expression of pro-apoptotic mammalian proteins. We have established a functional yeast survival screen that was used to isolate novel human anti-apoptotic genes overexpressed in treatment-resistant tumors. The screening of three different cDNA libraries prepared from m...

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Autors principals: Eißmann, Moritz, Schwamb, Bettina, Melzer, Inga Maria, Moser, Julia, Siele, Dagmar, Köhl, Ulrike, Rieker, Ralf Joachim, Wachter, David Lukas, Agaimy, Abbas, Herpel, Esther, Baumgarten, Peter, Mittelbronn, Michel, Rakel, Stefanie, Kögel, Donat, Böhm, Stefanie, Gutschner, Tony, Diederichs, Sven, Zörnig, Martin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661464/
https://ncbi.nlm.nih.gov/pubmed/23717670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064873
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