A Functional Yeast Survival Screen of Tumor-Derived cDNA Libraries Designed to Identify Anti-Apoptotic Mammalian Oncogenes

Yeast cells can be killed upon expression of pro-apoptotic mammalian proteins. We have established a functional yeast survival screen that was used to isolate novel human anti-apoptotic genes overexpressed in treatment-resistant tumors. The screening of three different cDNA libraries prepared from m...

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Bibliografiska uppgifter
Huvudupphovsmän: Eißmann, Moritz, Schwamb, Bettina, Melzer, Inga Maria, Moser, Julia, Siele, Dagmar, Köhl, Ulrike, Rieker, Ralf Joachim, Wachter, David Lukas, Agaimy, Abbas, Herpel, Esther, Baumgarten, Peter, Mittelbronn, Michel, Rakel, Stefanie, Kögel, Donat, Böhm, Stefanie, Gutschner, Tony, Diederichs, Sven, Zörnig, Martin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661464/
https://ncbi.nlm.nih.gov/pubmed/23717670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064873
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