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Characterization of DNA binding and pairing activities associated with the native SFPQ•NONO DNA repair protein complex

Nonhomologous end joining (NHEJ) is a major pathway for repair of DNA double-strand breaks. We have previously shown that a complex of SFPQ (PSF) and NONO (p54(nrb)) cooperates with Ku protein at an early step of NHEJ, forming a committed preligation complex and stimulating end-joining activity by 1...

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Détails bibliographiques
Publié dans:Biochem Biophys Res Commun
Auteurs principaux: Udayakumar, Durga, Dynan, William S.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497844/
https://ncbi.nlm.nih.gov/pubmed/25998385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.05.024
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