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Sequences in PSF/SFPQ mediate radioresistance and recruitment of PSF/SFPQ-containing complexes to DNA damage sites in human cells

PSF (gene name SFPQ) is a member of a small family of proteins with dual functions in RNA biogenesis and DNA repair. PSF and PSF-containing complexes stimulate double-strand break repair in cell free systems, most likely via direct interaction with the repair substrate. Prior in vitro studies are, h...

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Detalhes bibliográficos
Main Authors: Ha, Kyungsoo, Takeda, Yoshihiko, Dynan, William S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046316/
https://ncbi.nlm.nih.gov/pubmed/21144806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.11.009
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