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Conserved Residues Control Activation of Mammalian G Protein-Coupled Odorant Receptors

Odorant Receptor (OR) genes and proteins represent more than 2% of our genome and 4% of our proteome 25 and constitute the largest sub-group of G Protein-Coupled Receptors (GPCRs). The mechanism underlying OR activation remains poorly understood, as they do not share some of the highly conserved mot...

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Publicat a:J Am Chem Soc
Autors principals: de March, Claire A., Yu, Yiqun, Ni, Mengjue J., Adipietro, Kaylin A., Matsunami, Hiroaki, Ma, Minghong, Golebiowski, Jérôme
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497840/
https://ncbi.nlm.nih.gov/pubmed/26090619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b04659
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