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T cell signaling abnormalities contribute to aberrant immune cell function and autoimmunity

Systemic lupus erythematosus (SLE) is a prototype systemic autoimmune disease that results from a break in immune tolerance to self-antigens, leading to multi-organ destruction. Autoantibody deposition and inflammatory cell infiltration in target organs such as kidneys and brain lead to complication...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Moulton, Vaishali R., Tsokos, George C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497749/
https://ncbi.nlm.nih.gov/pubmed/25961450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78087
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