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T cell signaling abnormalities contribute to aberrant immune cell function and autoimmunity
Systemic lupus erythematosus (SLE) is a prototype systemic autoimmune disease that results from a break in immune tolerance to self-antigens, leading to multi-organ destruction. Autoantibody deposition and inflammatory cell infiltration in target organs such as kidneys and brain lead to complication...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4497749/ https://ncbi.nlm.nih.gov/pubmed/25961450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78087 |
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