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Checkpoints that control B cell development

B cells differentiate from pluripotent hematopoietic stem cells (pHSCs) in a series of distinct stages. During early embryonic development, pHSCs migrate into the fetal liver, where they develop and mature to B cells in a transient wave, which preferentially populates epithelia and lung as well as g...

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Bibliographic Details
Published in:J Clin Invest
Main Author: Melchers, Fritz
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497745/
https://ncbi.nlm.nih.gov/pubmed/25938781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78083
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