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Notch promotes recurrence of dormant tumor cells following HER2/neu-targeted therapy
Breast cancer mortality is principally due to recurrent tumors that arise from a reservoir of residual tumor cells that survive therapy. Remarkably, breast cancers can recur after extended periods of clinical remission, implying that at least some residual tumor cells pass through a dormant phase pr...
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| Published in: | J Clin Invest |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4497740/ https://ncbi.nlm.nih.gov/pubmed/25961456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74883 |
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