Hunk is required for HER2/neu-induced mammary tumorigenesis

Understanding the molecular pathways that contribute to the aggressive behavior of human cancers is a critical research priority. The SNF1/AMPK-related protein kinase Hunk is overexpressed in aggressive subsets of human breast, ovarian, and colon cancers. Analysis of Hunk(–/–) mice revealed that thi...

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Autors principals: Yeh, Elizabeth S., Yang, Thomas W., Jung, Jason J., Gardner, Heather P., Cardiff, Robert D., Chodosh, Lewis A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049391/
https://ncbi.nlm.nih.gov/pubmed/21393859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42928
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