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The Snf1-related kinase, Hunk, is essential for mammary tumor metastasis
We previously identified a SNF1/AMPK-related protein kinase, Hunk, from a mammary tumor arising in an MMTV-neu transgenic mouse. The function of this kinase is unknown. Using targeted deletion in mice, we now demonstrate that Hunk is required for the metastasis of c-myc-induced mammary tumors, but i...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2734880/ https://ncbi.nlm.nih.gov/pubmed/19717424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906993106 |
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