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SPSB1 Promotes Breast Cancer Recurrence by Potentiating c-MET Signaling

Breast cancer mortality is principally due to tumor recurrence; however, the molecular mechanisms underlying this process are poorly understood. We now demonstrate that the suppressor of cytokine signaling protein SPSB1 is spontaneously upregulated during mammary tumor recurrence and is both necessa...

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Detalhes bibliográficos
Main Authors: Feng, Yi, Pan, Tien-Chi, Pant, Dhruv K., Chakrabarti, Kristi R., Alvarez, James V., Ruth, Jason R., Chodosh, Lewis A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121738/
https://ncbi.nlm.nih.gov/pubmed/24786206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0548
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