SPSB1 Promotes Breast Cancer Recurrence by Potentiating c-MET Signaling

Breast cancer mortality is principally due to tumor recurrence; however, the molecular mechanisms underlying this process are poorly understood. We now demonstrate that the suppressor of cytokine signaling protein SPSB1 is spontaneously upregulated during mammary tumor recurrence and is both necessa...

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Bibliografiske detaljer
Main Authors: Feng, Yi, Pan, Tien-Chi, Pant, Dhruv K., Chakrabarti, Kristi R., Alvarez, James V., Ruth, Jason R., Chodosh, Lewis A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121738/
https://ncbi.nlm.nih.gov/pubmed/24786206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0548
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