Abnormal Accumulation of Collagen Type I Due to the Loss of Discoidin Domain Receptor 2 (Ddr2) Promotes Testicular Interstitial Dysfunction

BACKGROUND: Loss of functional allele for discoidin domain receptor 2 (Ddr2) results in impaired Leydig cell response to luteinizing hormone (LH), low testosterone production and arrested spermatogenesis in older male Ddr2(slie/slie) mice. However, the underlying mechanism responsible for this pheno...

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Publicat a:PLoS One
Autors principals: Zhu, Chu-chao, Tang, Bin, Su, Jin, Zhao, Hu, Bu, Xin, Li, Zhen, Zhao, Jie, Gong, Wei-dong, Wu, Zhi-qun, Yao, Li-bo, Li, Wei, Zhang, Yuan-qiang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497730/
https://ncbi.nlm.nih.gov/pubmed/26158267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131947
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