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Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance
The initiation of DNA replication in S phase requires the prior assembly of an origin recognition complex (ORC)-dependent pre-replicative complex on chromatin during G1 phase of the cell division cycle. In human cells, the Orc2 subunit localized to the nucleus as expected, but it also localized to c...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC449767/ https://ncbi.nlm.nih.gov/pubmed/15215892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600255 |
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