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Orc1 Binding to Mitotic Chromosomes Precedes Spatial Patterning during G(1) Phase and Assembly of the Origin Recognition Complex in Human Cells

Replication of eukaryotic chromosomes occurs once every cell division cycle in normal cells and is a tightly controlled process that ensures complete genome duplication. The origin recognition complex (ORC) plays a key role during the initiation of DNA replication. In human cells, the level of Orc1,...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kara, Nihan, Hossain, Manzar, Prasanth, Supriya G., Stillman, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424365/
https://ncbi.nlm.nih.gov/pubmed/25784553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.625012
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