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Orc1 Binding to Mitotic Chromosomes Precedes Spatial Patterning during G(1) Phase and Assembly of the Origin Recognition Complex in Human Cells
Replication of eukaryotic chromosomes occurs once every cell division cycle in normal cells and is a tightly controlled process that ensures complete genome duplication. The origin recognition complex (ORC) plays a key role during the initiation of DNA replication. In human cells, the level of Orc1,...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4424365/ https://ncbi.nlm.nih.gov/pubmed/25784553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.625012 |
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