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Orc1 Controls Centriole and Centrosome Copy Number in Human Cells

Centrosomes, each containing a pair of centrioles, organize microtubules in animal cells, particularly during mitosis. DNA and centrosomes are normally duplicated once prior to cell division to maintain optimal genome integrity. We report a new role for the Orc1 protein, a subunit of the Origin Reco...

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Hlavní autoři: Hemerly, Adriana S., Prasanth, Supriya G., Siddiqui, Khalid, Stillman, Bruce
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653626/
https://ncbi.nlm.nih.gov/pubmed/19197067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1166745
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