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TREK-1, a K(+) channel involved in neuroprotection and general anesthesia

TREK-1 is a two-pore-domain background potassium channel expressed throughout the central nervous system. It is opened by polyunsaturated fatty acids and lysophospholipids. It is inhibited by neurotransmitters that produce an increase in intracellular cAMP and by those that activate the Gq protein p...

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Heurteaux, C, Guy, N, Laigle, C, Blondeau, N, Duprat, F, Mazzuca, M, Lang-Lazdunski, L, Widmann, C, Zanzouri, M, Romey, G, Lazdunski, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2004
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC449762/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15175651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600234
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