TREK-1, a K(+) channel involved in neuroprotection and general anesthesia

TREK-1 is a two-pore-domain background potassium channel expressed throughout the central nervous system. It is opened by polyunsaturated fatty acids and lysophospholipids. It is inhibited by neurotransmitters that produce an increase in intracellular cAMP and by those that activate the Gq protein p...

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Vydáno v:	EMBO J
Hlavní autoři:	Heurteaux, C, Guy, N, Laigle, C, Blondeau, N, Duprat, F, Mazzuca, M, Lang-Lazdunski, L, Widmann, C, Zanzouri, M, Romey, G, Lazdunski, M
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Publishing Group 2004
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC449762/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15175651/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600234
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