TREK-1, a K(+) channel involved in neuroprotection and general anesthesia

TREK-1 is a two-pore-domain background potassium channel expressed throughout the central nervous system. It is opened by polyunsaturated fatty acids and lysophospholipids. It is inhibited by neurotransmitters that produce an increase in intracellular cAMP and by those that activate the Gq protein p...

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Publié dans:	EMBO J
Auteurs principaux:	Heurteaux, C, Guy, N, Laigle, C, Blondeau, N, Duprat, F, Mazzuca, M, Lang-Lazdunski, L, Widmann, C, Zanzouri, M, Romey, G, Lazdunski, M
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2004
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC449762/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15175651/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600234
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