Safety of valproic acid in patients with chronic obstructive pulmonary disease: a population-based cohort study

PURPOSE: Valproic acid is an anticonvulsant that also inhibits histone deacetylase (HDAC), a property that could worsen pulmonary function in patients with chronic obstructive pulmonary disease (COPD). The clinical significance of this property is unknown. We therefore compared the risk of COPD exac...

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Vydáno v:Pharmacoepidemiol Drug Saf
Hlavní autoři: Antoniou, Tony, Yao, Zhan, Camacho, Ximena, Mamdani, Muhammad M, Juurlink, David N, Gomes, Tara
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2015
Témata:
Original Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497617/
https://ncbi.nlm.nih.gov/pubmed/25656984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pds.3761
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